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Table 3 Regression analysis for the outcomes after PS matching

From: The impact of early target attainment of vancomycin in critically ill patients with confirmed Gram-positive infection: A retrospective cohort study

Outcomes

Early

Late

P-value

Hazard ratio (95%CI)

P-value$

30-day mortality, n (%)

22 (23.2)

25 (26.6)

0.5846^^

2.54 (1.24, 5.22)

0.01

    

Odds ratio (95%CI)

P-value$*

Developing of vancomycin resistance organism (s) (e.g. (VRSA, VISA), n (%)

3 (2.9)

3 (2.9)

0.9905**

4.28 (0.47, 38.8)

0.19

Eradication of microorganism within 4–5 days of vancomycin initiation, n (%)

72 (69.2)

70 (66.7)

0.6913^^

1.49 (0.75, 2.96)

0.25

Vancomycin induced acute kidney injury, n (%)

13 (12.5)

19 (18.1)

0.2614^^

2.59 (1.01, 6.65)

0.04

    

Beta coefficient (Estimates) (95%CI)

P-value $**

ICU length of stay (Days), Median (Q1, Q3) &

15.0 (9.00, 27.00)

13.0 (4.00, 24.00)

0.1802^

− 0.27 (− 0.58, 0.05)

0.10

Hospital length of stay (Days), Median (Q1, Q3) &

26.0 (14.00, 42.00)

24.0 (15.00, 44.00)

0.8722^

0.10 (− 0.22, 0.43)

0.54

  1. ^ Wilcoxon rank sum test is used to calculate the P-value
  2. ^^Chi-square test is used to calculate the P-value
  3. **Fisher Exact test is used to calculate the P-value
  4. &Denominator is patients who survived
  5. $Cox proportional hazards regression analysis is used to calculate hazard ratio (HR) and p-value
  6. $*Multivariate logistic regression analysis is used to calculate Odds ratio and p-value
  7. $**Generalized linear model is used to calculate beta coefficient (estimates) and p-value