Clinical features of HAdV-55 in children with respiratory tract infections: a retrospective case series and literature review

Table 1 Clinical data of five children with HAdV-55 infection in the children’s hospital of Chongqing medical university

Cases	Age range (years)	Sex	Admission time	Chief complaint	Length of hospital stay (days)	Co-detection	Primary diagnosis	Treatment	Complications	Outcome	Sequelae
Case 1	≤ 5	Male	2016/9/16	Fever 3 days, cough 2 days, wheezing, shortness of breath 1 day	3	Staphylococcus aureus	Severe pneumonia	Symptomatic supportive therapy	Respiratory failure, symptomatic diarrhea, hepatic impairment	Survival	None
Case 2	≤ 5	Male	2018/7/1	Fever 11 days	5	EBV, CMV	Bronchitis	Symptomatic supportive therapy	None	Survival	None
Case 3	≤ 5	Male	2019/7/21	Cough 1 month, aggravated with fever 5 days	9	Streptococcus pneumoniae, Haemophilus influenzae	Severe pneumonia	IVIG, Imipenem, and CPAP	Septicemia, respiratory failure, pleural effusion, pleurisy, hepatic impairment	Survival	None
Case 4	≤ 5	Female	2019/8/2	Cough more than 1 month, aggravated with intermittent fever 1 week	12	Streptococcus pneumoniae, syphilis suspected	Critical pneumonia	Methylprednisolone, IVIG, human albumin^a, erythrocyte suspension^b, cefazoxime, and IMV	Respiratory failure, toxic encephalopathy? Brain herniation, intracranial hemorrhage? Cerebral infarction? Pleural effusion, symptomatic diarrhea, coagulation disorders, hepatic impairment	Died
Case 5	≤ 5	Male	45,362	Cough more than 1 month with fever 6 days	4	None	Critical pneumonia	Methylprednisolone, IVIG, human albumin^a, erythrocyte suspension^b, Cefoperazone sulbactam sodium and IMV	ARDS, septicemia, pleural effusion, hepatic impairment	Died

EBV, Epstein-Barr virus; CMV, cytomegalovirus; IVIG, intravenous immunoglobulin; CPAP, continuous positive airway pressure; IMV, invasive mechanical ventilation
^a,Human albumin was administered to correct hypoalbuminemia
^b, erythrocyte suspension was utilized to manage anemia

ISSN: 1471-2334