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Table 3 ROC curve analysis by cytokines to predict the severity of SARS-CoV-2 infection

From: Peripheral blood cytokine profiles predict the severity of SARS-CoV-2 infection: an EPIC3 study analysis

Cytokines

Cutoff Value

AUC (95% CI)

Sensitivity

Specificity

Youden Index

GM-CSF

26.805

0.599 (0.507, 0.691)

0.595

0.619

0.214

HGF

235.305

0.649 (0.554, 0.744)

0.810

0.463

0.272

IL-1RA

1767.135

0.599 (0.504, 0.695)

0.500

0.706

0.206

IL-2

10.950

0.609 (0.516, 0.702)

0.667

0.575

0.242

IL-15

14.000

0.597 (0.505, 0.689)

0.643

0.588

0.230

IL-17A

12.305

0.601 (0.507, 0.695)

0.619

0.575

0.194

IL-27

71.405

0.593 (0.511, 0.675)

0.810

0.456

0.266

IP-10

200.975

0.707 (0.622, 0.791)

0.762

0.619

0.381

MCP-1

156.295

0.635 (0.534, 0.736)

0.595

0.694

0.289

VEGF-A

180.780

0.621 (0.529, 0.713)

0.786

0.500

0.286