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Table 1 Clinical details in the disease course

From: Refractory nontuberculous mycobacterial infection and potential hidden immunodeficiency related to RAG mutation and production of anti-interferon-α autoantibodies: a case report

Timepoint

Symptoms

Pathogens

Treatment

Therapeutic response

May 2022

Abdominal pain, fever, arthrodynia

Mycobacterium gordonae (lymph node)

Anti-NTM

Discharged in stable condition and continued anti-NTM therapy at a local hospital

June 2022 to July 2023

Edema, abdominal pain

Mycobacterium intracellulare (blood),

mycobacterium tuberculosis (ascites)

Anti-NTM, voriconazole, GC

Recurrent hospitalizations; temperature normalization with pulmonary lesion progression; clinical improvement following GC treatment

February 2024 to May 2024

Restricted movement of right upper limb and mouth, painful skin lesions

Suspected bacilli in a skin biopsy sample (anti-acid staining)

Methotrexate and anti-infection

Cutaneous and muscular symptoms resolution; presumed mortality

  1. GC: glucocorticoid