Univariate | Multivariate | ||||||||
---|---|---|---|---|---|---|---|---|---|
Characteristics | N | PY | Mortality rate (100 PY) | Crude HR | 95% CI | p-value | Adjusted HR | 95% CI | p-value |
Gender female | 10 | 80,71 | 11,2 | 1.34 | 0.54–3.30 | .5193 | - | - | - |
Age (years) | - | - | - | - | - | .5815 | - | - | - |
< 35 | 10 | 98.34 | 10.2 | 1 | - | - | - | - | - |
≥ 35 | 11 | 103.85 | 10.6 | 1.04 | 0.44–2.45 | - | - | - | - |
BMI (Kg/m2) | - | - | - | - | - | .1534 | - | - | - |
≥ 18 | 9 | 127.38 | 7.1 | 1 | - | - | - | - | - |
< 18 | 12 | 73.35 | 13.6 | 1.92 | 0.78–4.74 | - | - | - | - |
Karnofsky (%) | - | - | - | - | - | .2125 | - | - | - |
≥ 80 | 15 | 160.72 | 8.1 | 1 | - | - | - | - | - |
< 80 | 6 | 40.01 | 15.0 | 1.85 | 0.70–4.86 | - | - | - | - |
CD4 (/mm3) | - | - | - | - | .0421 | - | - | - | |
≥ 100 | 6 | 104.46 | 5.7 | 1 | - | - | - | - | - |
< 100 | 15 | 97.27 | 15.4 | 2.66 | 1.03–6.88 | - | - | - | - |
Log10 HIV viral load | - | - | - | - | - | .3138 | - | - | - |
< 5 log10 | 3 | 52,42 | 5,7 | 1 | - | - | - | - | - |
≥ 5 log10 | 18 | 148,31 | 10,8 | 1.88 | 0.54–6.46 | - | - | - | - |
Hemoglobin (g/dL) | - | - | - | - | - | .0466 | - | - | - |
≥ 9 | 9 | 138.75 | 6.5 | 1 | - | - | - | - | - |
< 9 | 12 | 61.97 | 16.1 | 2.49 | 1.01–6.14 | - | - | - | - |
Tuberculosis anatomical site | - | - | - | - | - | .1460 | - | - | - |
Pulmonary | 10 | 138.39 | 7.2 | 1 | - | - | - | - | - |
Mixed | 8 | 37.49 | 18.7 | 2.579 | 0.98–6.77 | - | - | - | - |
Extra pulmonary | 3 | 24.84 | 8.1 | 1.101 | 0.24–5.02 | - | - | - | - |
Cavitation | - | - | - | - | - | .2422 | - | - | .0073 |
No | 12 | 141.63 | 8.5 | 1 | - | - | 1 | - | - |
Yes | 3 | 16.52 | 18.2 | 2.12 | 0.60–7.53 | - | 7.92 | 1.74–35.94 | - |
Bilateral locations | - | - | - | - | - | .1509 | - | - | .5475 |
No | 14 | 102.39 | 13.7 | 1 | - | 1 | - | - | |
Yes | 7 | 99.8 | 7.0 | 0.51 | 0.20–1.27 | - | 0.64 | 0.15–2.67 | - |
Cavitation or bilateral location | - | - | - | - | - | .8658 | - | - | - |
No | 12 | 102.15 | 11.7 | 1 | - | - | - | - | - |
Yes | 9 | 100.04 | 9.0 | 0.92 | 0.37–2.27 | - | - | - | - |
Xpert MTB/RIF positivity level | - | - | - | - | - | .3421 | - | - | - |
Negative | 9 | 72.51 | 11.0 | 1 | - | - | - | - | - |
Very low or low | 5 | 72.36 | 5.5 | 0.50 | 0.15–1.66 | - | - | - | - |
Medium or high | 6 | 43.00 | 14.0 | 1.26 | 0.44–3.65 | - | - | - | - |
Smear positivity grade | - | - | - | - | - | .5460 | - | - | .2963 |
Negative | 13 | 115.95 | 10.3 | 1 | - | - | 1 | - | - |
Scanty or 1 + | 5 | 48.51 | 8.2 | 0.72 | 0.23–2.25 | - | 0.61 | 0.13–2.78 | - |
2 + or 3 + | 2 | 39.28 | 5.1 | 0.45 | 0.10–2.019 | - | 0.15 | 0.01–1.61 | - |
TB culture and time to culture positivity | - | - | - | - | - | .5471 | - | - | - |
Negative culture | 11 | 92.19 | 7.6 | 1 | - | - | - | - | - |
≤ 14 days | 1 | 32.44 | 0.0 | 0.00 | - | - | - | - | - |
> 14 days | 8 | 42.94 | 14.0 | 1.84 | 0.61–5.48 | - | - | - | - |
LAM result | - | - | - | - | - | .1139 | - | - | .0389 |
Negative | 3 | 70.63 | 4.2 | 1 | - | - | 1 | - | - |
Positive | 10 | 63.77 | 12.5 | 2.91 | 0.77–10.99 | - | 5.53 | 1.09–28.06 | - |
ART allocation | - | - | - | - | - | .6801 | - | - | - |
Efavirenz | 10 | 25.16 | 4.0 | 1 | - | - | - | - | - |
Raltégravir | 11 | 25.68 | 4.3 | 1.19 | 0.51–2.76 | - | - | - | - |