Table 3 Factors associated with severe morbidity among people living with HIV with tuberculosis: univariate and multivariate analysis

Gender female

1.15

0.75–1.76

.5117

-

-

-

Age (years)

-

-

.7197

-

-

-

< 35

1

-

-

-

-

-

≥ 35

0.92

0.60–1.40

-

-

-

-

BMI (Kg/m2)

-

-

.0389

-

-

-

 ≥ 18

1

-

-

-

-

-

 < 18

1.56

1.02–2.40

-

-

-

-

Karnofsky (%)

-

-

.3876

-

-

-

≥ 80

1

-

-

-

-

-

< 80

1.25

0.75–2.07

-

-

-

-

CD4 (/mm3)

-

-

.0003

-

-

.0709

≥ 100

1

-

-

-

-

-

< 100

2.23

1.45–3.44

-

1.86

0.94–3.64

-

Log10 HIV viral load

-

-

.0459

-

-

-

< 5 log10

1

-

-

-

-

-

≥ 5 log10

1.69

1.01–2.85

-

-

-

-

Hemoglobin (g/dL)

-

-

.6322

-

-

-

≥ 9

1

-

-

-

-

-

< 9

1.11

0.71–1.74

-

-

-

-

Tuberculosis anatomical site

-

-

.0566

-

-

-

 Pulmonary

1

-

-

1

-

-

 Mixed

1.18

0.68–2.03

-

-

-

-

 Extra pulmonary

2.06

1.14–3.74

-

-

-

-

Cavitation

-

-

.2272

-

-

.2499

 No

1

-

-

1

-

-

 Yes

0.59

0.25–1.38

-

0.46

0.12–1.71

-

Bilateral locations

-

-

.5799

-

-

.3941

 No

1

-

-

1

-

-

 Yes

0.89

0.60–1.32

-

1.31

0.70–2.44

-

Cavitation or bilateral location

-

-

.3761

-

-

-

 No

1

-

-

-

-

-

 Yes

0.84

0.57–1.23

-

-

-

Xpert MTB/RIF positivity level

-

.7737

-

-

-

 Negative

1

-

-

1

-

-

 Very low or low

1.17

0.71–1.92

-

-

-

-

 Medium or high

0.99

0.56–1.76

-

-

-

-

Smear positivity grade

-

-

.1462

-

-

.0824

 Negative

1

-

-

1

-

-

 Scanty or 1 + 

1.61

0.98–2.65

-

2.17

1.06–4.42

-

 2 + or 3 + 

1.02

0.57–1.81

-

1.11

0.46–2.67

-

TB culture and time to culture positivity

-

-

.6228

-

-

-

 Negative culture

1

-

-

1

-

-

≤ 14 days

1.48

0.65–3.36

-

-

-

-

> 14 days

1.00

0.64–1.56

-

-

-

-

LAM result

-

-

 < .0001

-

-

.0323

 Negative

1

-

-

1

-

-

 Positive

2.90

1.70–4.93

-

2.04

1.06–3.92

-