Skip to main content

Table 3 Daily drug dosage by patient weight (above 14 years old)

From: Non-inferiority stepped wedge cluster randomized controlled trial on all-oral shorter regimens for rifampicin resistant/multidrug-resistant TB in Pakistan – a study protocol

Drug

Weight-based daily dose

Formulation

30–35 kg

36–45 kg

46–55 kg

56–70 kg

 > 70 kg

Usual upper daily dose

Bedaquiline

 

100 mg tab

4 tabs od first two weeks, then 2 tabs od M/W/F for 22 weeks

400 mg

Levofloxacin

 

250 mg tab

3

3

4

4

4

1.5 g

500 mg tab

1.5

1.5

2

2

2

1.5 g

750 mg tab

1

1

1.5

1.5

1.5

1.5 g

Ethionamide

15–20 mg/kg

250 mg tab

2

2

3

3

4

1 g

Clofazimine

 

50 mg cps or tab

2

2

2

2

2

100 mg

100 mg cps or tab

1

1

1

1

1

100 mg

Pyrazinamide

20–30 mg/kg

400 mg tab

3

4

4

4

5

 

500 mg tab

2

3

3

3

4

 

Isoniazid (high dose)

10–15 mg/kg

300 mg tab

1.5

1.5

2

2

2

 

Ethambutol

15–25 mg/kg

400 mg tab

2

2

3

3

3

 

Linezolid

 

600 mg tab

 < 15 years

 < 15 years

1

1

1

1.2 g

  1. Adapted from https://iris.who.int/bitstream/handle/10665/311389/9789241550529-eng.pdf