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Table 3 Bivariate and multivariable logistic regression analysis of patients with tuberculosis

From: Tuberculosis mortality and drug resistance among patients under TB treatment before and during COVID-19 in Burundi: a case–control study

Models

 

Bivariate models

 

Multivariate Model

Conditions

N

OR

95% CI

p

aOR

95% CI

p

Socio-demographic

       

Period

       

 Before C19

222

Ref

  

Ref

  

 During C19

140

1.67

[1.09, 2.57]

0.018

1.83

[1.01, 3.40]

0.051

Education level

       

 University

34

Ref

  

Ref

  

 Primary or less

219

2.06

[0.99, 4.50]

0.059

3.930

[1.38, 12.03]

0.013

 Secondary

109

1.74

[0.79, 3.95]

0.176

2.457

[0.83, 07.72]

0.112

Residence

       

 Rural

93

Ref

  

Ref

  

 Urban

269

2.37

[1.46, 3.90]

 < 0.001

4.13

[1.88,09.46]

0.001

Living conditions

       

Prior incarceration

       

 No

343

Ref

  

Ref

  

 Yes

19

3.99

[1.42,14.24]

0.016

2.01

[0.38,13.47]

0.406

Collective residence

       

 No

325

Ref

  

Ref

  

 Yes

37

3.49

[1.66, 8.07]

0.002

2.33

[0.83, 6.89]

0.115

Occupation1

       

 Empoyed

53

Ref

  

Ref

  

 Unemployed

309

2.94

[1.58, 5.72]

 < 0.001

4.31

[1.71,11.75]

0.003

Household size

       

 ≤ 6

273

Ref

  

Ref

  

 > 6

89

3.94

[2.35, 6.83]

 < 0.001

6.31

[3.13,13.32]

 < 0.001

Persons by room

       

 1–2

194

Ref

  

Ref

  

 3 + 

168

1.34

[0.88, 2.02]

0.171

1.86

[0.94, 3.77]

0.080

Public transport

       

 No

180

Ref

  

Ref

  

 Yes

182

1.70

[1.13, 2.59]

0.012

2.14

[1.12, 4.16]

0.023

Clinical conditions

N

OR

95% CI

p

aOR

95% CI

p

TB history

       

 No

286

Ref

  

Ref

  

 Yes

76

3.92

[2.25, 7.08]

 < 0.001

2.19

[0.02, 264.9]

0.746

PTB close contact

       

 No

287

Ref

  

Ref

  

 Yes

75

3.72

[2.14, 6.73]

 < 0.001

0.51

[0.01,34.44]

0.764

MDR-TB close contact

       

 No

306

Ref

  

Ref

  

 Yes

56

13.81

[5.88,40.55]

 < 0.001

36.07

[12.58,1269]

 < 0.001

Tobacco smoking

       

 No

282

Ref

  

Ref

  

 Yes

80

4.33

[2.51, 7.81]

 < 0.001

3.88

[0.25,114.79]

0.356

Alcohol

       

 No

286

Ref

  

Ref

  

 Yes

76

3.92

[2.25, 7.08]

 < 0.001

1.26

[0.12, 10.89]

0.835

Diabetes

       

 No

346

Ref

  

Ref

  

 Yes

16

4.59

[1.45,20.28]

0.019

12.97

[2.64, 84.15]

0.003

Nutritional status

       

 Normal

144

Ref

  

Ref

  

 M.malnutrition

129

0.74

[0.21, 2.42]

0.616

1.36

[0.26, 6.66]

0.706

 S.malnutrition

89

1.07

[0.69, 1.65]

0.761

0.68

[0.35, 1.32]

0.256

Irregularity to T3

       

 No

297

Ref

  

Ref

  

 Yes

65

3.82

[2.19, 6.90]

 < 0.001

2.21

[0.61, 8.26]

0.229

Visits before TB Dx

       

 1

57

Ref

  

Ref

  

 2 + 

315

2.49

[1.39, 4.63]

 < 0.001

1.33

[0.73, 2.44]

0.355

Clinical condition at treatment start

     

 Stable

201

Ref

  

Ref

  

 Unstable

161

1.40

[0.92, 2.13]

0.113

1.41

[0.75, 2.67]

0.049

Treatment/supporter

       

 Yes

187

Ref

  

Ref

  

 No

175

1.34

[0.88, 2.02]

0.172

2.28

[1. 02, 5.28]

 < 0.001

HIV Status

       

 Negative

235

Ref

  

Ref

  

 Positive

127

3.92

[2.25, 7.08]

 < 0.001

-

-

-