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Table 2 Tick bites and erythema Migrans, disseminated borreliosis, antibiotic treatment, vaccination, comorbidities, and concomitant medication

From: Persistent self-reported health complaints in Norwegians who attribute their symptoms to tick bites or tick-borne disease– a cross-sectional controlled study

 

Cases

Controls

p-value

Tick bites and erythema migrans

   

Tick-bite more than twice

306 (73.0)

2013 (72.0)

0.652

Tick-bite last year

148 (35.3)

918 (32.9)

0.322

Erythema migrans twice or more

69 (16.7)

188 (6.7)

< 0.001

Disseminated borreliosis

   

Neuroborreliosis

97 (22.5)

17 (0.6)

< 0.001

Borrelia arthritis

49 (11.4)

8 (0.3)

< 0.001

TBE*

10 (2.3)

0 (0.0)

< 0.001

Other Bb infection

86 (19.9)

38 (1.4)

< 0.001

Tick-borne disease not specified

48 (11.2)

18 (0.6)

< 0.001

One or more episodes of disseminated

borreliosis

220 (50.2)

76 (2.7)

< 0.001

No previous borreliosis

Antibiotic treatment and vaccination

73 (17.8)

2117 (75.8)

< 0.001

More than two antibiotic treatments against tick-borne disease

168 (41.7)

109(4.0)

< 0.001

One antibiotic treatment

154 (38.2)

278 (10.3)

< 0.001

No antibiotic treatments

81 (20.1)

2318 (85.7)

< 0.001

Fully vaccinated against TBE

26 (6.7)

73 (2.6)

< 0.001

Comorbidities and concomitant medication

   

Comorbidities**

177 (42.1)

656 (23.4)

< 0.001

Concomitant medication***

148 (35.3)

701 (25.0)

< 0.001

  1. * Tick-borne encephalitis virus infection
  2. ** Comorbidities are defined as two or more diseases or medical conditions and is outlined in Table 3
  3. *** More than one concomitant medication against a medical condition
  4. Fractions of people exposed in the column and given percent (%)
  5. P-values calculated using the chi-square or Fisher’s exact test, when appropriate. NA means not applicable